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This result is suggestive of the constitutive activation of LKB1/AMPK pathway in the livers of KO mice

While there is a theoretical risk that CP antibodies could enhance disease via ADE, case reports in SARS-CoV and MERS-CoV outbreaks showed that CP therapy was safe and was associated with improved clinical outcomes 89,90

10.1016/j.joim.2020.01.008 236 LaneD

When combined with mast cell-stabilizing peptides like KPV, stress management can produce synergistic improvements that neither approach achieves alone