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On these bases, protecting the ER via the administration of antioxidants or activation of peroxisome proliferator-activated receptor (PPAR) has been suggested as promising avenues against hepatic steatosis ( Studies in rodents show the existence of a link between ERS and regulation of hepatic iron metabolism both in ASH and NASH models mainly due to the capacity of ferrous iron to catalyze the production of hydroxyl radical (OH ) from H 2 O 2 , deriving by peroxisomal -oxidation ( in vivo , and establish if a certain factor is exactly the cause or the effect of NASH

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Crocodilian oil, rich in polyunsaturated fatty acids, has been shown to support mitochondrial function and enhance cerebral energy production, suggesting potential cognitive and neuroprotective benefits (44)