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Description Why 5-Amino-1MQ Is Redefining Lipid Metabolism Research Selective NNMT inhibitor -35% fat mass in 11 days without appetite reduction (preclinical model) Enzymatic Target NNMT Inhibitor Selective inhibition of nicotinamide N-methyltransferase (IC50 = 1.2 M)

Intended Use: In-vitro enzyme inhibition studies Cell culture research on NAD+ metabolism In-vivo preclinical research with IACUC approval NNMT biology investigation Academic and institutional research only NOT Intended For: Human consumption or administration Therapeutic treatment or diagnosis Dietary supplementation or metabolic enhancement Athletic performance enhancement Veterinary therapeutic use Non-research applications Safety Protocols: Standard laboratory PPE (lab coat, gloves, safety glasses) Handle in well-ventilated areas Avoid dust inhalation (use fume hood for weighing) Follow institutional chemical hygiene guidelines Proper waste disposal per regulations Consult SDS for detailed safety information

doi: 10.1016/j.biopha.2015.07.034, 56

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