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It has since been understood that when applied to the skin or ingested, Tranexamic Acid reduces the production of melanin by blocking melanocytes, the cells that produce pigment and are responsible for conditions like hyperpigmentation and melasma

In another study, vemurafenib-loaded lipid nanocomplexes in melanoma model revealed downregulation of Ki-67 and BRD4 and significant tumor necrosis [133]