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Similarly, adolescents with MDD had lower serum TRP levels and increased QA levels and KYN/TRP rations relative to healthy controls [39]

PubMed Central PMCID: PMC3368579 10.1155/2012/965385 [DOI] [PMC free article] [PubMed] [Google Scholar] 119.Hornung N., Ellingsen T., Stengaard-Pedersen K

Rapamycin has demonstrated significant neuroprotective effects by enhancing autophagic flux, which aids in clearing proteotoxic aggregates associated with various neurodegenerative disorders