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4-(pyridin-2-yldiazenyl)phenol (200 mg, 1 mmol) was dissolved in a mixture of DMF (10 mL), potassium carbonate (207 mg, 1.5 mmol), and potassium iodide(183 mg, 1.1 mmol)

Metallothionein-1 as a biomarker of altered redox metabolism in hepatocellular carcinoma cells exposed to sorafenib

Integrating trace element metabolism from the cell to the whole organism

Depending on the severity of the liver damage, patients can present with a range of symptoms, from being initially asymptomatic to having overt signs of liver failure, including jaundice, confusion, ascites, nausea and vomiting