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The SDS requires further investigation with ethnically diverse samples and different age groups and settings, establishing its test-retest stability, invariance across different cultures, and its predictive validity, by exploring its relationship with other relevant psychological constructs, such as anxiety and mood disorders or attention deficit hyperactivity disorder (ADHD) (272), especially in clinical samples by identifying how the frequency and compulsiveness of smartphone use and the impact of this cognitive-emotive construct may contribute to the deterioration or alleviation of symptoms of various disorders (273)

Notably, Ascaris Argonautes that associate with small RNAs targeting repetitive sequences (AsWAGO-1, AsWAGO-2, and AsNRDE-3) do not have the catalytic tetrad for slicing activity