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Additional testing may be considered for people with a family history of premature heart disease, metabolic risk, abnormal cholesterol results, known cardiovascular disease, or uncertainty after standard testing: ApoB, Lp(a), and hs-CRP may help reveal particle burden, inherited risk, and inflammation that are not fully captured by LDL cholesterol alone

doi: 10.1186/s12951-024-02711-1 191 McInnesIBSchettG

Inhibiting nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy, a type of selective autophagy for the degradation of ferritin by lysosomes, increases iron storage and limits ferroptosis in cancer cells 48,49 (Fig

In newborns, symptoms can mimic those of sepsis, making diagnosis challenging