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Modulation of the Hsp response was shown to be beneficial for diseases associated with protein aggregation since it reduces the protein aggregation itself and diminishes cellular stress and apoptosis ( G93A mice, a fALS model, while reducing the abundance of ubiquitin-positive aggregates in the motor neurons ( Ambroxol, a beta-glucocerebrosidase 2 (GBA2) inhibitor originally indicated as a generic expectorant and mucolytic drug to treat respiratory tract infectious disorders (Nobata et al., 2006), has been recently found to be a potential drug candidate for ALS treatment

However, clinical experience clearly indicates its beneficial effect, particularly for nocturnal pain, when combined with gabapentin

B12, along with B6 and folate, help metabolize homocysteine levels

An overview of pathogen recognition receptors for innate immunity in dental pulp