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Intracellular antioxidant system of melanocytes Due to the high risk of melanocytes exposure to harmful and prooxidant factors of the external environment, these cells are characterized by naturally well-developed complex antioxidant systems, including enzymatic and non-enzymatic antioxidants (Fig

Inosine monophosphate dehydrogenase (IMPDH), the rate-limiting enzyme in de novo guanine nucleotide biosynthesis, has gained particular attention (Hackstein and Thomson, 2004

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