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Moreover, in a lung cancer mouse model, the peptide N-acetylglucosaminyltransferase 3 suppressed AKT phosphorylation triggered by c-MET, leading to decreased synthesis of the chemokine CXCL3, which is essential for MDSC attraction [82]

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113 On the other hand, with ligation of the inferior caval vein occlusion we made a recapitulation of Virchow

Despite these efforts, the technique still suffers from limited depth sensitivity, which is crucial for instance in measurements of the cerebral hemodynamics, limiting its translation to the clinics