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Collected the references: Lixia Ju, Jun Xiang

Stimulation of M1 enhances excitability within intracortical circuits, thalamic relays, and descending modulatory pathways, producing analgesic effects partly mediated by endogenous opioids (22)

This strain repaired the mucosal barrier by upregulating the expression of mucosal barrier proteins occludin and ZO-1, alleviating gastritis (Xu et al., 2023)

Emerging Topicals: Topical and transdermal peptide delivery is an active area of research, particularly for localized applications and sustained-release models