glutathione-responsive prodrug

glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of Redox-Responsive Polyprodrugs: Recent Innovations in

Name: glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of Redox-Responsive Polyprodrugs: Recent Innovations in
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SKU: 85438404997
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Redox Responsive Polyprodrugs: Recent Innovations in Reduction and Oxidation Responsive Drug Delivery Systems Chemistry of Materials PDF) Glutathione responsive iNOS inhibiting polymeric prodrug for targeted Inhibition of angiogenesis Glutathione Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy ACS Nano A GSH Activatable Theranostic Prodrug Based on Photoinduced Electron Transfer for Cancer Fluorescence Imaging and Therapy

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Description

Emerging CAR-macrophage (CAR-M) platforms, exemplified by anti-HER2 CAR-Ms, not only mediate the direct phagocytosis of tumor cells but also potentiate antigen presentation and pro-inflammatory cytokine release (187)

Taking advantage of the fact that they can be reduced by thiols that exist in the cell cytoplasm, such as glutathione, ADCs have been engineered to be conjugated to the disulfide linkers that remain stable in the circulation and selectively release drugs in the cytoplasm