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Pharmacological inhibition of PRMTs compromises DNA repair and overcomes resistance to anti-cancer agents such as gemcitabine and PARP inhibitors, as demonstrated in preclinical and early-phase clinical studies [193,194,195,196]

The acronym MIC stands for the three core ingredients: methionine (an essential amino acid), inositol (a sugar alcohol involved in cell signaling), and choline (an essential nutrient for liver health)

Their minimum inhibitory concentrations (MIC) ranged from 1.67 to 3.33 mg/mL for bacteria and from 6.67 to 13.3 mg/mL for fungi

Acknowledgments The authors would like to thank the IEU GWAS database and the FinnGen database for making the pooled data publicly available and giving us the opportunity to learn from it