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Environ Int 131:104989

Responses to Hypoxia: How Fructose Metabolism and Hypoxia-Inducible Factor-1a Pathways Converge in Health and Disease

10 g of mouse anti-HA IgG (Clone 16B12, Biolegend) was diluted in 200 L PBS-T and bound to 50 L of Invitrogen Protein G Dynabeads for 30 min at RT in a reaction with rotation

Repeated oral dose of OTA induced oxidative stress in mice kidneys, which was concluded from increased lipid peroxidation parameters (conjugated dienes and trienes, and malondialdehyde), downregulation of glutathione S-transferase and, upregulation of glutathione peroxidase genes