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Moreover, the ubiquitin E3 ligase ZNRF1 (zinc and ring finger 1) has been demonstrated to be associated with Wallerian degeneration after SCI (Araki and Milbrandt, Once the acute inflammatory response to SCI has resolved, spinal cord neurons engage in a process of rewiring (neuroplasticity) and in efforts to extend new axons across the injured region (neuroregeneration)

" [2] GHK peptide may also be released from the breakdown of another extracellular matrix-binding protein involved in regulating cell shape and proliferation, called SPARC (Secreted Protein, Acidic, and Rich in Cysteine)

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F., & Hardin, D