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Neurologic clinics, 31(2), 477-489

Health status considerations: Generally healthy adults with physician clearance, individuals without contraindications (pregnancy, active malignancy, severe organ disease), those willing to commit to proper administration protocols and monitoring, and patients who understand the research-purposes-only status and informed consent requirements

A decrease in IF production can occur when autoimmune antibodies attack the cells of the stomach that produce IF, causing them to become damaged or destroyed

Some of these problems include neurological disorders, brain atrophy, demyelination, delayed cognitive development and growth, mental retardation, lack of emotional and communicative responses, lack of smiling and willingness to play, extreme fatigue, vomiting, tremors and convulsions, gait and motor coordination disorders, severe megaloblastic anemia, thrombocytopenia, pancytopenia, which can lead to coma, respiratory failure, and death