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These include: Infection Soreness at the injection site (usually short-lived) Diabetic patients may see transient increases in their blood glucose with corticosteroid injections Patients with poorly controlled blood pressure may see a transient increase in their blood pressure Changes in skin pigmentation around the injection site (can be seen with corticosteroid injections, particularly if near the skin surface) Post-injection flare, a short-lived increase in pain and inflammation occurring shortly after injection caused by a reaction to the injected material Pseudo-sepsis, a rare allergic type reaction to viscosupplementation that can result in significant pain and swelling which can, at times, mimic infection

Duration of Treatment and Maintenance Phase Treatment for moderate neuropathy with B12 can last 3-6 months

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