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Monaco D, Fatnassi M, Padalino B, Aub L, Khorchani T, Hammadi M, Lacalandra GM

[9] For wound healing specifically, the evidence is stronger than for cosmetic anti-aging, because wound models involve measurable endpoints (wound closure rate, tissue tensile strength, histological analysis) in controlled animal studies

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However, accumulating evidence suggests that all LDH isoforms retain the inherent capacity to mediate pyruvate-to-lactate conversion accompanied by NAD+ regeneration, and that LDHA and LDHB can functionally compensate for each other under metabolic stress (44,45)