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Skeletal muscle tissue becomes a target for breakdown, particularly in patients who are not consuming adequate protein or engaging in resistance training

For optimal results, the recommended dosage of B12 typically involves injections of 1 ml, 2-3 times weekly, as advised by our physicians

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Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team