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Glutamine can act as an inducer of ferroptosis, promoting ferroptosis through its own hydrolysis, but this process requires cystine starvation [47]

The mechanistic and fate data generated by the research community must be used to inform a necessary evolution towards more nuanced, property-based regulations that consider parameters beyond mass concentration, such as surface area, reactivity, and transformation potential

Future studies should aim to standardize dosing protocols and assess a broader range of doses to clarify the optimal therapeutic window [121, 130, 137]

Similarly to agarose percentage, adding crosslinkers changes the pore size and rigidifies, or strengthens, the resulting beads (Figure 4)