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Beyond protein recruitment, m 5 C provides direct biophysical stabilization by enhancing nucleobase stacking and increasing the thermostability of hydrogen bonding with guanine [75, 76], These effects facilitate rRNA folding and positively regulate ribosomal function [77]

GSH dysregulation might cause global immune cell autophagy decline with increased generation of proinflammatory cytokines in aging, further provoked by mitochondrial ROS signaling (293)

10.1111/ene.13975 Eur J Neurol

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