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Total glutathione concentrations were highest in the bronchial versus the alveolar space (299), consistent with the bronchial features of asthma (such as airway hyperresponsiveness) and the nature of the inflammation in these subjects, which is primarily localized to the airways

Future developments will likely integrate real-time imaging, stimuli-responsive drug release, and personalized biomimetic designs to fully exploit ferroptosis vulnerabilities in clinical translation

NMR signals from some amino acid residues of PGRMC1 disappeared due to the paramagnetic relaxation effect of haem (Supplementary Figs 6b)