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Topical GHK-Cu produces negligible serum concentrations (less than 1% bioavailability) but creates a prolonged dermal reservoir, with peptide detectable in skin biopsies for 4896 hours

Poor storage can destroy your peptide before you even use it

Advanced delivery systems using GHK-Cu in ionic liquid microemulsion achieved hair follicle entry into early growth stages in 6 days versus 8 days for standard GHK-Cu and 9 days for minoxidil, representing approximately 3-fold improved local delivery

Moreover, SIRT1 inhibits FAS expression and lipid accumulation by deacetylating Liver Kinase B1 (LKB1), regulating hepatic lipid metabolism [31]