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Mn toxicity is closely related to its role in promoting the production of ROS within several cellular compartments, predominantly through the mitochondrial electron transport chain (ETC), NADPH oxidases, and the enzymatic activation of cytochrome P450, xanthine oxidase, and cyclooxygenases 1 and 2

Because of the availability of more robust genetic resources, most of these studies have thus far been focused on model dicot plants, such as Arabidopsis and alfalfa, but our knowledge on lignin modification-induced dwarfism in monocotyledonous grass species remains largely unexplored

doi: 10.3390/brainsci14030243

2017;5 doi: 10.1177/2326409817692359