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Traditionally, these co-chaperones are thought to interact with HSP70 molecules solely via the N-terminal J domain of HSP40s, without the involvement of other regionsparticularly the C-terminal domain and the intermediate glycine/phenylalanine-rich (GF) linker region

Hassler, R

Univariate and multivariable regression analyses were performed to detect associations between characteristics and outcomes

Moving forward, regulators and researchers must prioritize the development and validation of adolescent-specific scales, integrating input from patients, caregivers, and clinical experts to ensure accurate representation of treatment impacts in this unique population