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The results indicated that manganese reduced the protein and mRNA expression levels of EAAC1 and xCT

The acyl-CoA synthetase long-chain family member 3 (ACSL3), which is critical in converting fatty acids into fatty acyl-CoA esters, enables cancer cells in the lymph to incorporate oleic acid in the cell membrane to protect them from ferroptosis (62)

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A study that shows a reduction in histone-deacetylase activity in alveolar macrophages from cigarette smokers, which could explain the poor anti-inflammatory effects of corticosteroids in COPD