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Proceedings of the National Academy of Sciences, 115 (34), 201804764-E8085

Consistent supplementation with skin brightening supplements can help fade existing dark spots while preventing new ones from forming during the summer months

Valsartan was without grossly observable adverse effects at single oral doses up to 2000 mg/kg in rats and up to 1000 mg/kg in marmosets, except for the salivation and diarrhea in the rat and vomiting in the marmoset at the highest dose (60 and 37 times, respectively, the MRHD on a mg/m2 basis) (Calculations assume an oral dose of 320 mg/day and a 60 kg patient)