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In a 3-nitropropionic acid animal model of Huntingtons disease (HD), RES derivatives delayed the onset and reduced the severity of HD-like symptoms, improved locomotor activity, and protected against weight loss, with simultaneous enhancement of superoxide dismutase 2 (SOD2) expression in brain tissue and a decrease in circulating levels of interleukin-6 (IL-6), respectively [51]

The closest approach between the comet and the spacecraft happened on 4 November 2025