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Importantly, the majority of these experimental findings have been further corroborated in human NS workers, with clear differences compared to day workers observed across multiple biological mechanisms (including oxidative stress, immune dysfunction, inflammation, melatonin disruption, clock gene alterations, epigenetic changes, telomere attrition, and hormonal imbalances)

Traditional medicine systems have employed curcumin for centuries to address ailments such as wounds, infections, and digestive disorders [123]

Chronic diseases associated with the cell danger response and incomplete healing Autoinflammatory disorders Autism spectrum disorder (ASD) Alzheimers dementia Bipolar disorder Cancers and leukemias Chronic Fatigue Syndrome (ME/CFS) Chronic infections Bartonella, Lyme disease, Epstein-Barr virus Fibromyalgia Generalized anxiety disorder Hashimotos thyroiditis Inflammatory bowel diseases (Crohns and ulcerative colitis) Long COVID Migraines Mold related illness Multiple sclerosis Neuropathic pain syndromes Obsessive-compulsive disorder (OCD) PANS/PANDAS Parkinsons disease Post-treatment Lyme disease Postural orthostatic tachycardia syndrome (POTS) Psoriasis Rheumatoid arthritis Traumatic brain injury (TBI) All of these conditionsand morehave increased significantly in the past five decades