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Description

Trial data at the 2 mg/week dose (lower end of Phase 2) ran somewhat below the 4 mg+ doses

A recent study from our group demonstrated lower serum and nail selenium levels in boys aged 24 to 47 months with ASD compared to sex-matched controls (Mehta et al., 2021)

Disclosures: ATSUSHI UMEDA: EA Pharma Co., Ltd.: Employee, YASUKO OWADA: Nothing to Disclose, KENICHI FURIHATA: Kissei Pharmaceutical Company: Advisor, SHUICHI TSURUOKA: Nothing to Disclose, Atsushi Nakajima: Nothing to Disclose, RYOSUKE MIKAMI: Nothing to Disclose, MASAKAZE OAKU: Nothing to Disclose, TAKUYA YAMAMOTO: Nothing to Disclose, TETSUO YANO: Nothing to Disclose, YUJI KUMAGAI: Nothing to Disclose 593 DNA METHYLOME ANALYSIS REVEALS EPIGENETIC ALTERATION OF COMPLEMENT GENES IN ADVANCED MASLD Won Kim 1 Young Ho So 1 YONG JIN JUNG 1 Sae Kyung Joo 1 , 1 Boramae Medical Center Background: Blocking the complement system presents a promising strategy to impede the progression of metabolic dysfunction-associated steatotic liver disease (MASLD)