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Indeed, structural analysis of the K6:KRAS complex showed that a tripeptide motif, P42, W43 and F44, inserts into this SI/SII pocket in a manner that mimics the binding of known small molecules targeting this pocket

Sunitinib inhibits tumor growth and synergizes with cisplatin in orthotopic models of cisplatin-sensitive and cisplatin-resistant human testicular germ cell tumors