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3.1.1.6 Liver cancer Different evidence has shown that oxidative stress plays a potent role in the development of hepatic carcinogenesis by disrupting genetic material, the normal functioning of the cell, and by interfering with various pathways of cell signaling (Jain et al., 2020)

The current review summarizes the most current examples of leishmanicidal agents based on 4-aminoquinolines focusing the analysis on two essential aspects: (i) structureproperty relationship to identify the key pharmacophores and (ii) mode of action focused on key targets in parasite survival ( e.g