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2285-C CHOLESTEROL-ASSOCIATED LOCUS EHBP1 PROTECTS AGAINST NASH FIBROSIS Fanglin Ma and Bishuang Cai, Icahn School of Medicine at Mount Sinai Background: Elevated hepatic cholesterol content is frequently seen in human NASH and high-cholesterol diets have been found to promote NASH progression in mouse models

These include anticancer activity (breast carcinoma, prostatic cancer, hepatocellular carcinoma, lung cancer, renal cell carcinoma, bladder cancer and other cancers), anti-oxidant activity, antimicrobial activity, anti-inflammation activity, cardiovascular protection, neuroprotection, respiratory protection, digestive system protection, antidiabetic, liver and kidney protection, skin protection and other pharmacological activities (Figure 3)

However, some results differed between these studies, which could be explained by differences in tissue processing and immunostaining

A meta-analysis of randomized controlled trials