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Conversely, findings from national register-based studies suggest that the risk of mania may not be increased when antidepressants are combined with a mood stabiliser [29, 30]

A comprehensive safety panel of relevant blood markers was quantified from each study subject at the beginning of the study, at 3 days after first dosing and after 2 weeks of GlyNAC consumption, including blood pressure, glucose, insulin, creatinine, Alkaline Phosphatase (ALP), Alanine Aminotransferase (ALT), among others (Supplementary Table S3