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It is likely that GSHee exerts its effects in nave rats by increasing levels of GSH and metabolites (-glutamylcysteinyl and cysteine) in cells (e.g., neurons) in which GSH 53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74 and the metabolites 82,105,106,107,108 affect a number of biological processes

Furthermore, where applicable, four separate nematodes were analysed for each consecutive section, and two to six ROIs were acquired per nematode

Notably, glioblastoma cells exhibit high GPX4 expression, making them inherently resistant to ferroptosis, as GPX4 suppression correlates with increased ferroptotic sensitivity [64] (Fig

doi: 10.1038/s41522-025-00763-1 236 ZhangW.DengX.ZhouX.HaoY.LiY