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Description

While it was ruled unlikely that the event was related to the peptide, the investigators decided to halt any future trials

R.LeedmanP

These two ghrelin receptor complexes display pronounced outward displacements of TM6 cytoplasmic end (~8 , measured at C of H258 6.30 ), the hallmark of GPCR activation, and ~3 inward shift of cytoplasmic end of TM7 (measured at C of Y323 7.53 ) (Fig