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These problems are associated with a series of immune responses induced by the binding of ACE2 receptor, which is widely present in the reproductive organs (such as ovary, uterus, vagina, and placenta), while the processes of follicular development, ovulation, angiogenesis are regulated by ACE2 receptor and angiotensin (Siyu et al., 2024)

(1991) J

The current standard treatment for patients with breast cancer includes the combination of surgery, radiation, hormone therapy and chemotherapy drugs, such as anthracyclines, cyclophosphamide, taxanes and platinum compounds [2, 3]

Apoptosis Three different pathways can cause the apoptotic process: the intrinsic pathway through mitochondria, the extrinsic pathway through death receptors, and the intrinsic pathway through the endoplasmic reticulum