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It is tempting to speculate that an attenuated anti-oxidant response with elevated ROS in COPD [21, 22, 28, 36] may lead to an increased oxidant burden, possibly contributing to the observed mitochondrial defects in bronchial epithelial cells from COPD patients [6, 32, 37]

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Hence CAMPCO an Indian farmer co-operative is recommending IARC to re-classify arecanut from Group I to Group II-B [31] During pregnancy [edit] Women who chew areca nut formulations, such as paan , during pregnancy significantly increase adverse outcomes for the baby

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