glutathione and parasites

glutathione and parasites Thioredoxin Reductase from Schistosoma mansoni: An Essential Parasite Enzyme a Key Drug Target Loss of vitamin C biosynthesis

Name: glutathione and parasites Thioredoxin Reductase from Schistosoma mansoni: An Essential Parasite Enzyme a Key Drug Target Loss of vitamin C biosynthesis
Brand: iglepidom.org
SKU: 87753655311
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Loss of vitamin C biosynthesis protects from the pathology of a parasitic infection PNAS Selenium and protozoan parasitic infections: selenocompounds and selenoproteins potential Parasitology Research Springer Nature Link Peroxide antimalarial drugs target redox homeostasis in Plasmodium falciparum infected red blood cells bioRxiv Parasites, nutrition, immune responses, and biology of metabolic tissues PMC

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Description

Specifically, 15-LOX selectively catalyzes the oxidation of phosphatidylethanolamine-arachidonic acid, generating 15-hydroperoxy-eicosa-tetra-enoyl-phosphatidylethanolamine (15-HpETE-PE), which serves as a signal for ferroptosis (79, 80)

The redox signaling can regulate the canonical Wnt/-catenin signaling pathway by activating TCF 17,38,39 and that NTAPP impacts on the biological targets by generating the various oxidation molecules 10,11,12,30,35,40