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Springer London, pp 8392 Cabas-Mora G, Daza A, Soto-Garca N et al (2024) Peptipedia v2.0: a peptide sequence database and user-friendly web platform

In human skin fibroblasts, Nrf2-driven antioxidant enzyme expression translated into: Reduced intracellular ROS Improved mitochondrial membrane potential Protection against senescence-associated cell damage [36] In human gingival and periodontal stem cells, Epitalon significantly reduced aging biomarkers such as p16 and p21, decreased ROS levels, and preserved mitochondrial function, even under stress [42]