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Recently, a genetic screen revealed two lipid metabolism regulatorslysophosphatidylcholine acyltransferase 3 (LPCAT3) and acyl-CoA synthetase long-chain family member 4 (ACSL4)that drive ferroptosis via an accumulation of oxidized phospholipids in the cell membrane [40]

Both positive and negative mode ion polarity spectra were acquired with a mass range of m/z = 751125

Aberrant glucose metabolism is a characteristic of cancer and the TME produces metabolic challenges to T cells, thus impairing the antitumor immune response [45]

Carnitine performs many other physiological functions, including the conversion of ketoacid analogues of the branched-chain amino acids valine, leucine, and isoleucine, an extremely important function in fasting, before, and during exercise