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Microbial glutathione S-transferases

Furthermore, we revealed that co-administration of EPI and F--DDB-derivative (ip, once every other day for 14 days) significantly increased the therapeutic efficacy of EPI (2.0 mg/kg) or F--DDB-derivative (20.0 mg/kg) in mice harboring MDA-MB-468 cell xenografts without additional cardiotoxicity compared to that in EPI monotherapy group

doi: 10.1038/nature13148 127 Santana-CodinaNGikandiAManciasJD

4.2 EMS promotes inflammation and oxidative stress in GCs Inflammation and oxidative stress can impair oocyte quality and potentially cause follicular atresia