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SKU: 88039449608
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2.13.1.2 E693del (Osaka) mutation The APP E693-Tg (Osaka) mouse model, which carries the Osaka mutation (APP695) under the control of the mouse prion promoter, expressed comparable levels of mutant human APP and endogenous mouse APP

Int J Cancer 2009

This specific form of B12 is an essential cofactor for the enzyme methylmalonyl-CoA mutase, which is a critical step in feeding fatty acids and amino acids into the Krebs cycle for ATP production