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Hormonal signals profoundly influence these metabolic fluxes: insulin and insulin-like growth factor 1 (IGF-1) are anabolic hormones that promote glucose uptake and utilization and activate the mTOR pathway, a central regulator of cell growth and protein synthesis [61]

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The disclosure includes embodiments in which more than one, or the entire group members are present in, employed in or otherwise relevant to a given product or process