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4.2 Autophagy in the dysbiosis: a trigger for periodontal ferroptosis In periodontitis, the dysbiotic microbiota is not a bystander in ferroptosis but actively regulates host autophagy pathways through the secretion of virulence factors

All other chemicals used in the study were of analytical reagent grade

10.3779/j.issn.1009-3419.2007.06.02 42 GaoZ

22 In the liver of WT mice, phosphorylation of JNK which is activated by TNF- was increased by Con A administration, whereas its phosphorylation did not increase in the liver of Gpx1 KO mice injected with Con A (Figure 3b)