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They increase the concentration of endogenous catecholamines at synapses in both the brain and heart

All reagents and experiments conducted in this study are compliant with the institutional biological safety committee (SPROTO202200000081) of the University of Arkansas for Medical Sciences

In contrast to the delayed colonization of the brain, fungal burden increased in the lungs, liver, spleen, and kidneys of mice infected with gsh2 mutants 26 days post-infection, suggesting that gsh2 -infected mice likely succumbed to cryptococcal pneumonia and/or visceral organ damage rather than brain infection (Extended Data Figs

Natarajan P, Young R, Stitziel NO, Padmanabhan S, Baber U, Mehran R, et al