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To assess cell viability, 10 l CellTiter-Fluor (Promega) was added to black plates and incubated for 30 min in the dark before fluorescence was measured at 7-mm depth (gain 100)

Additionally, the APOE-4 allele is the strongest genetic risk factor for both early- and late-onset AD, contributing to increased amyloid deposition and disease progression (Kim et al., 2009)

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On the other hand, there is no doubt that in rat models of cocaine use disorder (CUD), NAC did not change cocaine reward, but effectively reduced escalation of drug intake, cocaine-seeking, and reinstatement behaviors [8, 10, 14, 19, 21, 50,51,52,53,54,55,56,57] (Table 1)