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And I, like I eat such a consistent diet with very little change that if I add in something that's very different, I will like notice if something is off, I'm like a very good controlled experiment basically

The removed plasma is discarded

The fourth and final stage is severe/late stage AD during which the disease takes over the entirety of the cerebral cortex and amyloid plaques and NFTs dramatically increase in number (De-Paula et al., 2012