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The two major transcription factors: i) the NFB upregulates the pro-oxidant mediators, and ii) the Nrf2 activates the antioxidant responses 622

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( 3.3 Responsive drug release from GO@GSH-FA nanoparticles We systematically analyzed the release kinetics of GSH from GO@GSH-FA nanoparticles in the presence of 0, 0.5 and 5 mM H 2 O 2 to simulate different oxidative stress conditions